CADM1 - Gene info - The Human Protein Atlas

Gene name

CADM1 (HGNC Symbol)

Synonyms

BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1

Description

Cell adhesion molecule 1 (HGNC Symbol)

Entrez gene summary

Chromosome

Cytoband

q23.3

Chromosome location (bp)

115169218 - 115504957

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000182985 (version 78.38)

Entrez gene

23705

UniProt

Q9BY67 (UniProt - Evidence at protein level)

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CADM1-001

ENSP00000395359
ENST00000452722

Q9BY67
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Q9BY67 [Direct mapping]
Cell adhesion molecule 1
X5D8W0 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 isoform D {ECO:0000313|EMBL:AHW56433.1}
F5H8J9 [Target identity:24%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
Q6MZK6 [Target identity:19%; Query identity:100%]
Putative uncharacterized protein DKFZp686F1789 {ECO:0000313|EMBL:CAE46024.1}
F5H0H5 [Target identity:17%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006915 [apoptotic process]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0007283 [spermatogenesis]
GO:0008037 [cell recognition]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0030154 [cell differentiation]
GO:0030165 [PDZ domain binding]
GO:0034329 [cell junction assembly]
GO:0034332 [adherens junction organization]
GO:0042271 [susceptibility to natural killer cell mediated cytotoxicity]
GO:0042803 [protein homodimerization activity]
GO:0045216 [cell-cell junction organization]
GO:0045954 [positive regulation of natural killer cell mediated cytotoxicity]
GO:0050715 [positive regulation of cytokine secretion]
GO:0051606 [detection of stimulus]
GO:0070062 [extracellular vesicular exosome]

442

48.5

Yes

CADM1-002

ENSP00000439176
ENST00000542447

Q9BY67
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Q9BY67 [Direct mapping]
Cell adhesion molecule 1
F5H8J9 [Target identity:26%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:19%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}
H1ZZW4 [Target identity:16%; Query identity:100%]
CADM1 protein {ECO:0000313|EMBL:CCD32615.1}

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414

45.6

Yes

CADM1-003

ENSP00000329797
ENST00000331581

Q9BY67
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Q9BY67 [Direct mapping]
Cell adhesion molecule 1
X5D7A8 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 isoform A {ECO:0000313|EMBL:AHW56435.1}
F5H8J9 [Target identity:23%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:16%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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GO:0001889 [liver development]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006915 [apoptotic process]
GO:0007155 [cell adhesion]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0007283 [spermatogenesis]
GO:0007416 [synapse assembly]
GO:0007420 [brain development]
GO:0008021 [synaptic vesicle]
GO:0008037 [cell recognition]
GO:0009826 [unidimensional cell growth]
GO:0016021 [integral component of membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016338 [calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules]
GO:0030154 [cell differentiation]
GO:0030165 [PDZ domain binding]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0034329 [cell junction assembly]
GO:0034332 [adherens junction organization]
GO:0042271 [susceptibility to natural killer cell mediated cytotoxicity]
GO:0042803 [protein homodimerization activity]
GO:0043005 [neuron projection]
GO:0045202 [synapse]
GO:0045216 [cell-cell junction organization]
GO:0045954 [positive regulation of natural killer cell mediated cytotoxicity]
GO:0050715 [positive regulation of cytokine secretion]
GO:0050839 [cell adhesion molecule binding]
GO:0051606 [detection of stimulus]
GO:0060348 [bone development]
GO:0070062 [extracellular vesicular exosome]

471

51.5

Yes

CADM1-005

ENSP00000439817
ENST00000537058

Q9BY67
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Q9BY67 [Direct mapping]
Cell adhesion molecule 1
X5DQR8 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 isoform B {ECO:0000313|EMBL:AHW56432.1}
F5H8J9 [Target identity:24%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:17%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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453

49.6

Yes

CADM1-006

ENSP00000440322
ENST00000536727

X5DQS5
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X5DQS5 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000440322}; Cell adhesion molecule 1 isoform C {ECO:0000313|EMBL:AHW56437.1}
F5H8J9 [Target identity:24%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:17%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

443

48.6

Yes

CADM1-008

ENSP00000442387
ENST00000545380

F5H8J9
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F5H8J9 [Target identity:26%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:19%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}
H1ZZW4 [Target identity:16%; Query identity:100%]
CADM1 protein {ECO:0000313|EMBL:CCD32615.1}

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

413

45.4

Yes

CADM1-010

ENSP00000442227
ENST00000543249

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

189

21.1

CADM1-013

ENSP00000439847
ENST00000543540

F5H0H5
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F5H0H5 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

8.9

CADM1-014

ENSP00000439696
ENST00000545094

F5H125
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F5H125 [Target identity:100%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439696}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

182

20.5

CADM1-015

ENSP00000442001
ENST00000542450

F5H8J9
Show all » « Hide

F5H8J9 [Target identity:99%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:71%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

111

12.7

CADM1-201

ENSP00000483648
ENST00000612235

F5H8J9
Show all » « Hide

F5H8J9 [Target identity:31%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:22%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}
H1ZZW4 [Target identity:19%; Query identity:100%]
CADM1 protein {ECO:0000313|EMBL:CCD32615.1}

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

346

38.8

CADM1-202

ENSP00000483793
ENST00000612471

F5H8J9
Show all » « Hide

F5H8J9 [Target identity:29%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:21%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}
H1ZZW4 [Target identity:18%; Query identity:100%]
CADM1 protein {ECO:0000313|EMBL:CCD32615.1}

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

373

41.7

CADM1-203

ENSP00000484516
ENST00000616271

F5H8J9
Show all » « Hide

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

412

45.7

CADM1-204

ENSP00000482840
ENST00000621043

F5H8J9
Show all » « Hide

F5H8J9 [Target identity:25%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
F5H0H5 [Target identity:18%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

430

47.6

CADM1-205

ENSP00000482924
ENST00000621709

F5H8J9
Show all » « Hide

F5H8J9 [Target identity:27%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442001}
Q6MZK6 [Target identity:20%; Query identity:100%]
Putative uncharacterized protein DKFZp686F1789 {ECO:0000313|EMBL:CAE46024.1}
F5H0H5 [Target identity:19%; Query identity:100%]
Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000439847}

Show » « Hide

Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

401

44.6

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.