CHST15

GENE INFORMATION

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Gene name

CHST15 (HGNC Symbol)

Synonyms

BRAG, GALNAC4S-6ST, KIAA0598

Description

Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 (HGNC Symbol)

Entrez gene summary

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

Chromosome

10

Cytoband

q26.13

Chromosome location (bp)

124007666 - 124093607

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000182022 (version 78.38)

Entrez gene

51363

UniProt

Q7LFX5 (UniProt - Evidence at protein level)

neXtProt

NX_Q7LFX5

Antibodypedia

CHST15 antibodies
 

PROTEIN VIEW

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CHST15-001
 
CHST15-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHST15-001 ENSP00000333947
ENST00000346248
Q7LFX5
Show all »
Show » Show » 561 64.9 No 1
CHST15-201 ENSP00000402394
ENST00000435907
Q7LFX5
Show all »
Show » Show » 561 64.9 No 1