AGTR2

GENE INFORMATION

? »

Gene name

AGTR2 (HGNC Symbol)

Synonyms

AT2, MRX88

Description

Angiotensin II receptor, type 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010]

Chromosome

X

Cytoband

q23

Chromosome location (bp)

116170722 - 116174972

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000180772 (version 78.38)

Entrez gene

186

UniProt

P50052 (UniProt - Evidence at protein level)

neXtProt

NX_P50052

Antibodypedia

AGTR2 antibodies
 

PROTEIN VIEW

? »
 
 
 
AGTR2-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGTR2-001 ENSP00000360973
ENST00000371906
P50052
Show all »
Show » Show » 363 41.2 No 7