CDC42EP4

GENE INFORMATION

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Gene name

CDC42EP4 (HGNC Symbol)

Synonyms

BORG4, CEP4, KAIA1777, MGC17125, MGC3740

Description

CDC42 effector protein (Rho GTPase binding) 4 (HGNC Symbol)

Entrez gene summary

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

73283624 - 73312175

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179604 (version 78.38)

Entrez gene

23580

UniProt

Q9H3Q1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H3Q1

Antibodypedia

CDC42EP4 antibodies
 

PROTEIN VIEW

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CDC42EP4-001
 
CDC42EP4-003
 
CDC42EP4-004
 
CDC42EP4-006
 
CDC42EP4-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC42EP4-001 ENSP00000338258
ENST00000335793
Q9H3Q1
Show all »
Show » Show » 356 38 No 0
CDC42EP4-003 ENSP00000404270
ENST00000439510
Q9H3Q1
Show all »
Show » Show » 286 30.2 No 0
CDC42EP4-004 ENSP00000463877
ENST00000579611
J3QQS6
Show all »
Show » 73 7.8 No 0
CDC42EP4-006 ENSP00000462231
ENST00000580315
J3KRZ9
Show all »
Show » Show » 127 14 No 0
CDC42EP4-009 ENSP00000464104
ENST00000581014
J3QR93
Show all »
Show » 79 8.5 No 0