SLC17A8

GENE INFORMATION

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Gene name

SLC17A8 (HGNC Symbol)

Synonyms

DFNA25, VGLUT3

Description

Solute carrier family 17 (vesicular glutamate transporter), member 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Chromosome

12

Cytoband

q23.1

Chromosome location (bp)

100357079 - 100422059

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179520 (version 78.38)

Entrez gene

246213

UniProt

Q8NDX2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NDX2

Antibodypedia

SLC17A8 antibodies
 

PROTEIN VIEW

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SLC17A8-001
 
SLC17A8-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC17A8-001 ENSP00000316909
ENST00000323346
Q8NDX2
Show all »
Show » Show » 589 65 No >9
SLC17A8-002 ENSP00000376715
ENST00000392989
Q8NDX2
Show all »
Show » Show » 539 59.1 No >9