MSC

GENE INFORMATION

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Gene name

MSC (HGNC Symbol)

Synonyms

ABF-1, bHLHa22

Description

Musculin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q13.3

Chromosome location (bp)

71841549 - 71844468

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178860 (version 78.38)

Entrez gene

9242

UniProt

O60682 (UniProt - Evidence at protein level)

neXtProt

NX_O60682

Antibodypedia

MSC antibodies
 

PROTEIN VIEW

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MSC-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MSC-001 ENSP00000321445
ENST00000325509
O60682
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