MAF

GENE INFORMATION

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Gene name

MAF (HGNC Symbol)

Synonyms

c-MAF

Description

V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Chromosome

16

Cytoband

q23.2

Chromosome location (bp)

79585843 - 79600714

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178573 (version 78.38)

Entrez gene

4094

UniProt

O75444 (UniProt - Evidence at protein level)

neXtProt

NX_O75444

Antibodypedia

MAF antibodies
 

PROTEIN VIEW

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MAF-001
 
MAF-002
 
MAF-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAF-001 ENSP00000327048
ENST00000326043
O75444
Show all »
Show » Show » 403 42 No 0
MAF-002 ENSP00000377019
ENST00000393350
O75444
Show all »
Show » Show » 373 38.5 No 0
MAF-003 ENSP00000455097
ENST00000569649
H3BP11
Show all »
Show » Show » 383 39.6 No 0