CA8

GENE INFORMATION

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Gene name

CA8 (HGNC Symbol)

Synonyms

CALS, CARP

Description

Carbonic anhydrase VIII (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q12.1

Chromosome location (bp)

60187347 - 60281412

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178538 (version 78.38)

Entrez gene

767

UniProt

P35219 (UniProt - Evidence at protein level)

neXtProt

NX_P35219

Antibodypedia

CA8 antibodies
 

PROTEIN VIEW

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CA8-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA8-001 ENSP00000314407
ENST00000317995
P35219
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