SPINK6

GENERAL INFORMATION

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Gene name

SPINK6

Gene description

Serine peptidase inhibitor, Kazal type 6

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (colon)
GTEx:Tissue enhanced (cerebellum, cervix, uterine, vagina)

Protein evidence

Evidence at protein level

Protein localization

Strong cytoplasmic staining was observed in lymphoid tissues. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA011039
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (colon)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum, cervix, uterine, vagina)

Organ

Expression



GENE INFORMATION

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Gene name

SPINK6 (HGNC Symbol)

Synonyms

BUSI2, MGC21394, UNQ844

Description

Serine peptidase inhibitor, Kazal type 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene. [provided by RefSeq, Aug 2010]

Chromosome

5

Cytoband

q32

Chromosome location (bp)

148202794 - 148215137

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178172 (version 78.38)

Entrez gene

404203

UniProt

Q6UWN8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6UWN8

Antibodypedia

SPINK6 antibodies


PROTEIN BROWSER

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ENST00000325630
 
ENST00000514389
 
ENST00000621437
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPINK6-001 ENSP00000324870
ENST00000325630
Q6UWN8
Show all »
Show » Show » 80 8.6 Yes 0
SPINK6-002 ENSP00000421119
ENST00000514389
D6RGX9
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Show » 41 4.5 Yes 0
SPINK6-201 ENSP00000481309
ENST00000621437
Q6UWN8
Show all »
Show » Show » 80 8.6 Yes 0