DDX10

GENE INFORMATION

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Gene name

DDX10 (HGNC Symbol)

Synonyms

HRH-J8

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q22.3

Chromosome location (bp)

108665025 - 108940930

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178105 (version 78.38)

Entrez gene

1662

UniProt

Q13206 (UniProt - Evidence at protein level)

neXtProt

NX_Q13206

Antibodypedia

DDX10 antibodies
 

PROTEIN VIEW

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DDX10-001
 
DDX10-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX10-001 ENSP00000314348
ENST00000322536
Q13206
Show all »
Show » Show » 875 100.9 No 0
DDX10-003 ENSP00000432032
ENST00000526794
E9PIF2
Show all »
Show » Show » 835 96.5 No 0