RPS27

GENE INFORMATION

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Gene name

RPS27 (HGNC Symbol)

Synonyms

MPS-1, MPS1, S27

Description

Ribosomal protein S27 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153990759 - 153992150

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177954 (version 78.38)

Entrez gene

6232

UniProt

P42677 (UniProt - Evidence at protein level)

neXtProt

NX_P42677

Antibodypedia

RPS27 antibodies
 

PROTEIN VIEW

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RPS27-001
 
RPS27-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPS27-001 ENSP00000357555
ENST00000368567
P42677
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Show » Show » 84 9.5 No 0
RPS27-002 ENSP00000376341
ENST00000392558
Q5T4L4
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Show » Show » 66 7.4 No 0