ZBTB38 - Gene info - The Human Protein Atlas

Gene name

ZBTB38 (HGNC Symbol)

Synonyms

CIBZ, FLJ35036, PPP1R171, ZNF921

Description

Zinc finger and BTB domain containing 38 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010]

Chromosome

Cytoband

q23

Chromosome location (bp)

141324213 - 141449792

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177311 (version 78.38)

Entrez gene

253461

UniProt

Q8NAP3 (UniProt - Evidence at protein level)

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZBTB38-001

ENSP00000426387
ENST00000514251

Q8NAP3
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Q8NAP3 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
J3KPK6 [Target identity:100%; Query identity:99%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000372635}
D6RBC4 [Target identity:64%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000424254}
B3KST1 [Target identity:50%; Query identity:100%]
cDNA FLJ36882 fis, clone BLADE2000340, highly similar to Zinc finger and BTB domain-containing protein 38 {ECO:0000313|EMBL:BAG52843.1}
Q9H6F0 [Target identity:27%; Query identity:100%]
CDNA: FLJ22332 fis, clone HRC05753 {ECO:0000313|EMBL:BAB15309.1}
D6R9I1 [Target identity:17%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422081}
D6RE69 [Target identity:12%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426931}
D6RJE1 [Target identity:12%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}
D6R9U6 [Target identity:9%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:9%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RHD1 [Target identity:9%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6RC86 [Target identity:7%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:5%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:2%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Transcription factors
Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0003676 [nucleic acid binding]
GO:0003700 [sequence-specific DNA binding transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0008327 [methyl-CpG binding]
GO:0042803 [protein homodimerization activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0072562 [blood microparticle]

1195

134.3

ZBTB38-002

ENSP00000426931
ENST00000509842

D6RE69
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D6RE69 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426931}
D6RJE1 [Target identity:97%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}
D6RHD1 [Target identity:78%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6R9U6 [Target identity:74%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:72%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:62%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:46%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:22%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

150

16.9

ZBTB38-005

ENSP00000424254
ENST00000509883

D6RBC4
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D6RBC4 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000424254}
D6R9I1 [Target identity:27%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422081}
D6RE69 [Target identity:19%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426931}
D6RJE1 [Target identity:18%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}
D6RHD1 [Target identity:15%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6R9U6 [Target identity:14%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:14%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:12%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:8%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:4%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0046872 [metal ion binding]

771

85.8

ZBTB38-006

ENSP00000422757
ENST00000513570

D6RAC4
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D6RAC4 [Target identity:98%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:48%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

ZBTB38-007

ENSP00000406955
ENST00000441582

Q8NAP3
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Predicted intracellular proteins
Transcription factors
Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

1195

134.3

ZBTB38-010

ENSP00000421037
ENST00000507722

D6RHD1
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D6RHD1 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6R9U6 [Target identity:94%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:91%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:79%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:58%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:28%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

118

13.3

ZBTB38-012

ENSP00000422051
ENST00000503809

D6R9J6
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D6R9J6 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

3.9

ZBTB38-013

ENSP00000426288
ENST00000513258

D6RGK1
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D6RGK1 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:87%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:63%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:31%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

108

12.3

ZBTB38-016

ENSP00000425705
ENST00000510338

D6RJE1
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D6RJE1 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}
D6RHD1 [Target identity:80%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6R9U6 [Target identity:76%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:73%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:64%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:47%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:23%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

146

16.4

ZBTB38-017

ENSP00000422347
ENST00000504673

D6RC86
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D6RC86 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:73%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:36%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

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GO:0005515 [protein binding]

10.8

ZBTB38-018

ENSP00000422081
ENST00000510726

D6R9I1
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D6R9I1 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422081}
D6RE69 [Target identity:71%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426931}
D6RJE1 [Target identity:69%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}
D6RHD1 [Target identity:56%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}
D6R9U6 [Target identity:52%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:51%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:44%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:32%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:16%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

210

23.7

ZBTB38-019

ENSP00000422894
ENST00000509813

D6R9U6
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D6R9U6 [Target identity:100%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}
D6RGK1 [Target identity:97%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}
D6RC86 [Target identity:84%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}
D6RAC4 [Target identity:62%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}
D6R9J6 [Target identity:30%; Query identity:100%]
Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}

Show » « Hide

Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

GO:0005515 [protein binding]

111

12.5

ZBTB38-201

ENSP00000372635
ENST00000321464

Q8NAP3
Show all » « Hide

Show » « Hide

Predicted intracellular proteins
Transcription factors
Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

Show » « Hide

1195

134.3

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.