DEFB104A

GENE INFORMATION

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Gene name

DEFB104A (HGNC Symbol)

Synonyms

DEFB-4, DEFB104, DEFB4

Description

Defensin, beta 104A (HGNC Symbol)

Entrez gene summary

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

7836471 - 7841242

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000176782 (version 78.38)

Entrez gene

140596

UniProt

Q8WTQ1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WTQ1

Antibodypedia

DEFB104A antibodies
 

PROTEIN VIEW

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DEFB104A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB104A-001 ENSP00000320813
ENST00000314265
Q8WTQ1
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