LPL

GENE INFORMATION

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Gene name

LPL (HGNC Symbol)

Synonyms

LIPD

Description

Lipoprotein lipase (HGNC Symbol)

Entrez gene summary

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p21.3

Chromosome location (bp)

19901717 - 19967258

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175445 (version 78.38)

Entrez gene

4023

UniProt

P06858 (UniProt - Evidence at protein level)

neXtProt

NX_P06858

Antibodypedia

LPL antibodies
 

PROTEIN VIEW

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LPL-001
 
LPL-003
 
LPL-004
 
LPL-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPL-001 ENSP00000309757
ENST00000311322
P06858
Show all »
Show » Show » 475 53.2 Yes 0
LPL-003 ENSP00000428237
ENST00000524029
E5RJI0
Show all »
Show » 130 14.5 Yes 0
LPL-004 ENSP00000428557
ENST00000522701
E5RHN7
Show all »
Show » 106 11.7 Yes 0
LPL-006 ENSP00000428496
ENST00000520959
E7EW14
Show all »
Show » 115 12.9 No 0