BANF1

GENE INFORMATION

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Gene name

BANF1 (HGNC Symbol)

Synonyms

BAF

Description

Barrier to autointegration factor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

66002079 - 66004149

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175334 (version 78.38)

Entrez gene

8815

UniProt

O75531 (UniProt - Evidence at protein level)

neXtProt

NX_O75531

Antibodypedia

BANF1 antibodies
 

PROTEIN VIEW

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BANF1-001
 
BANF1-002
 
BANF1-003
 
BANF1-004
 
BANF1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BANF1-001 ENSP00000310275
ENST00000312175
O75531
Show all »
Show » Show » 89 10.1 No 0
BANF1-002 ENSP00000416128
ENST00000445560
O75531
Show all »
Show » Show » 89 10.1 No 0
BANF1-003 ENSP00000431785
ENST00000530204
E9PJJ8
Show all »
Show » Show » 28 3 No 0
BANF1-004 ENSP00000433760
ENST00000533166
O75531
Show all »
Show » Show » 89 10.1 No 0
BANF1-005 ENSP00000432867
ENST00000527348
O75531
Show all »
Show » Show » 89 10.1 No 0