NPPA

GENE INFORMATION

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Gene name

NPPA (HGNC Symbol)

Synonyms

ANP, PND

Description

Natriuretic peptide A (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009]

Chromosome

1

Cytoband

p36.22

Chromosome location (bp)

11845709 - 11848345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175206 (version 78.38)

Entrez gene

4878

UniProt

P01160 (UniProt - Evidence at protein level)

neXtProt

NX_P01160

Antibodypedia

NPPA antibodies
 

PROTEIN VIEW

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NPPA-001
 
NPPA-002
 
NPPA-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NPPA-001 ENSP00000365663
ENST00000376480
P01160
Show all »
Show » Show » 151 16.4 Yes 0
NPPA-002 ENSP00000365659
ENST00000376476
B0ZBE8
Show all »
Show » Show » 101 10.8 No 0
NPPA-201 ENSP00000483195
ENST00000610706
B0ZBE8
Show all »
Show » Show » 152 16.6 Yes 0