BRMS1

GENE INFORMATION

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Gene name

BRMS1 (HGNC Symbol)

Synonyms

DKFZP564A063

Description

Breast cancer metastasis suppressor 1 (HGNC Symbol)

Entrez gene summary

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.2

Chromosome location (bp)

66337333 - 66345125

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174744 (version 78.38)

Entrez gene

25855

UniProt

Q9HCU9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HCU9

Antibodypedia

BRMS1 antibodies
 

PROTEIN VIEW

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BRMS1-001
 
BRMS1-002
 
BRMS1-005
 
BRMS1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BRMS1-001 ENSP00000353042
ENST00000359957
Q9HCU9
Show all »
Show » Show » 246 28.5 No 0
BRMS1-002 ENSP00000396052
ENST00000425825
G5E9I4
Show all »
Show » Show » 290 33.7 No 0
BRMS1-005 ENSP00000433740
ENST00000530756
E9PJF5
Show all »
Show » 244 28.3 No 0
BRMS1-008 ENSP00000431510
ENST00000524699
Show » 267 31.1 No 0