TLR10

GENE INFORMATION

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Gene name

TLR10 (HGNC Symbol)

Synonyms

CD290

Description

Toll-like receptor 10 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Chromosome

4

Cytoband

p14

Chromosome location (bp)

38772239 - 38782990

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174123 (version 78.38)

Entrez gene

81793

UniProt

Q9BXR5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXR5

Antibodypedia

TLR10 antibodies
 

PROTEIN VIEW

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TLR10-001
 
TLR10-002
 
TLR10-003
 
TLR10-004
 
TLR10-201
 
TLR10-202
 
TLR10-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TLR10-001 ENSP00000308925
ENST00000308973
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1
TLR10-002 ENSP00000424923
ENST00000508334
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1
TLR10-003 ENSP00000421483
ENST00000506111
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1
TLR10-004 ENSP00000427606
ENST00000502321
D6RHW6
Show all »
Show » Show » 94 10.9 No 0
TLR10-201 ENSP00000354459
ENST00000361424
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1
TLR10-202 ENSP00000478206
ENST00000613579
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1
TLR10-203 ENSP00000478985
ENST00000622002
Q9BXR5
Show all »
Show » Show » 811 94.6 Yes 1