DMRT2

GENE INFORMATION

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Gene name

DMRT2

Synonyms

Description

Doublesex and mab-3 related transcription factor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]

Chromosome

9

Cytoband

p24.3

Chromosome location (bp)

1050354 - 1057552

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000173253 (version 78.38)

Entrez gene

10655

UniProt

Q9Y5R5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y5R5

Antibodypedia

DMRT2 antibodies
 

PROTEIN VIEW

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DMRT2-001
 
DMRT2-002
 
DMRT2-003
 
DMRT2-004
 
DMRT2-201
 
DMRT2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DMRT2-001 ENSP00000350865
ENST00000358146
Q9Y5R5
Show all »
Show » Show » 561 61.8 No 0
DMRT2-002 ENSP00000397494
ENST00000412350
Q9Y5R5
Show all »
Show » Show » 226 24.5 No 1
DMRT2-003 ENSP00000259622
ENST00000259622
Q9Y5R5
Show all »
Show » Show » 226 24.5 No 1
DMRT2-004 ENSP00000371690
ENST00000382255
Q9Y5R5
Show all »
Show » Show » 226 24.5 No 1
DMRT2-201 ENSP00000305785
ENST00000302441
Show » 405 45.2 No 0
DMRT2-202 ENSP00000371686
ENST00000382251
Q9Y5R5
Show all »
Show » Show » 561 61.8 No 0