CCL19

GENERAL INFORMATION

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Gene name

CCL19

Gene description

Chemokine (C-C motif) ligand 19

Protein class

Cancer-related genes
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (appendix, lymph node, tonsil)
GTEx:Tissue enhanced (small intestine)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (appendix, lymph node, tonsil)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (small intestine)

Organ

Expression



GENE INFORMATION

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Gene name

CCL19 (HGNC Symbol)

Synonyms

CKb11, ELC, exodus-3, MIP-3b, SCYA19

Description

Chemokine (C-C motif) ligand 19 (HGNC Symbol)

Entrez gene summary

This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]

Chromosome

9

Cytoband

p13.3

Chromosome location (bp)

34689567 - 34691277

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172724 (version 78.38)

Entrez gene

6363

UniProt

Q99731 (UniProt - Evidence at protein level)

neXtProt

NX_Q99731

Antibodypedia

CCL19 antibodies


PROTEIN BROWSER

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ENST00000311925
 
ENST00000378800
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL19-001 ENSP00000308815
ENST00000311925
Q99731
Show all »
Show » Show » 98 11 Yes 0
CCL19-003 ENSP00000368077
ENST00000378800
Q5VZ75
Show all »
Show » Show » 104 11.3 Yes 0