RCAN2

GENE INFORMATION

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Gene name

RCAN2 (HGNC Symbol)

Synonyms

DSCR1L1, ZAKI-4

Description

Regulator of calcineurin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Chromosome

6

Cytoband

p12.3

Chromosome location (bp)

46220736 - 46491972

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172348 (version 78.38)

Entrez gene

10231

UniProt

Q14206 (UniProt - Evidence at transcript level)

neXtProt

NX_Q14206

Antibodypedia

RCAN2 antibodies
 

PROTEIN VIEW

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RCAN2-001
 
RCAN2-002
 
RCAN2-003
 
RCAN2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RCAN2-001 ENSP00000329454
ENST00000330430
Q14206
Show all »
Show » Show » 197 22 No 0
RCAN2-002 ENSP00000360425
ENST00000371374
Q14206
Show all »
Show » Show » 243 27.3 No 0
RCAN2-003 ENSP00000305223
ENST00000306764
Q14206
Show all »
Show » Show » 243 27.3 No 0
RCAN2-201 ENSP00000384317
ENST00000405162
Q86YJ0
Show all »
Show » Show » 224 24.9 No 1