FRMD3

GENE INFORMATION

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Gene name

FRMD3 (HGNC Symbol)

Synonyms

EPB41L4O, MGC20553

Description

FERM domain containing 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Chromosome

9

Cytoband

q21.32

Chromosome location (bp)

83242990 - 83538546

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172159 (version 78.38)

Entrez gene

257019

UniProt

A2A2Y4 (UniProt - Evidence at transcript level)

neXtProt

NX_A2A2Y4

Antibodypedia

FRMD3 antibodies
 

PROTEIN VIEW

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FRMD3-001
 
FRMD3-002
 
FRMD3-003
 
FRMD3-005
 
FRMD3-006
 
FRMD3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FRMD3-001 ENSP00000365621
ENST00000376438
A2A2Y4
Show all »
Show » Show » 556 63.9 No 1
FRMD3-002 ENSP00000365617
ENST00000376434
A2A2Y4
Show all »
Show » Show » 362 40.7 No 1
FRMD3-003 ENSP00000328615
ENST00000328788
A2A2Y4
Show all »
Show » Show » 213 23.9 No 1
FRMD3-005 ENSP00000412719
ENST00000431299
Q5JV61
Show all »
Show » Show » 140 15.8 No 0
FRMD3-006 ENSP00000303508
ENST00000304195
A2A2Y4
Show all »
Show » Show » 597 68.8 No 1
FRMD3-201 ENSP00000484839
ENST00000621208
A2A2Y4
Show all »
Show » Show » 553 63.7 No 1