RRM2

GENE INFORMATION

? »

Gene name

RRM2

Synonyms

Description

Ribonucleotide reductase M2 (HGNC Symbol)

Entrez gene summary

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

10122328 - 10131419

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171848 (version 78.38)

Entrez gene

6241

UniProt

P31350 (UniProt - Evidence at protein level)

neXtProt

NX_P31350

Antibodypedia

RRM2 antibodies
 

PROTEIN VIEW

? »
 
 
 
RRM2-001
 
RRM2-010
 
RRM2-013
 
RRM2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RRM2-001 ENSP00000353770
ENST00000360566
P31350
Show all »
Show » Show » 449 51.1 No 1
RRM2-010 ENSP00000419177
ENST00000474701
C9JXC1
Show all »
Show » Show » 289 33.8 No 0
RRM2-013 ENSP00000302955
ENST00000304567
P31350
Show all »
Show » Show » 389 44.9 No 1
RRM2-201 ENSP00000484183
ENST00000615152
P31350
Show all »
Show » Show » 449 51.1 No 1