CLSTN1

GENE INFORMATION

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Gene name

CLSTN1 (HGNC Symbol)

Synonyms

CDHR12, CSTN1, KIAA0911

Description

Calsyntenin 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Chromosome

1

Cytoband

p36.22

Chromosome location (bp)

9729026 - 9824526

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171603 (version 78.38)

Entrez gene

22883

UniProt

O94985 (UniProt - Evidence at protein level)

neXtProt

NX_O94985

Antibodypedia

CLSTN1 antibodies
 

PROTEIN VIEW

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CLSTN1-001
 
CLSTN1-002
 
CLSTN1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLSTN1-001 ENSP00000366513
ENST00000377298
O94985
Show all »
Show » Show » 981 109.8 Yes 1
CLSTN1-002 ENSP00000354997
ENST00000361311
O94985
Show all »
Show » Show » 971 108.6 Yes 1
CLSTN1-003 ENSP00000401934
ENST00000435891
Q5SR54
Show all »
Show » Show » 782 88 No 1