LRG1

GENERAL INFORMATION

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Gene name

LRG1

Gene description

Leucine-rich alpha-2-glycoprotein 1

Protein class

Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (liver)
GTEx:Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissues, high abundance in hepatocytes with distinct positivity in plasma.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 2 antibodies.
HPA001888 , HPA001889
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Rectum

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (liver)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (liver)

Organ

Expression



GENE INFORMATION

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Gene name

LRG1 (HGNC Symbol)

Synonyms

LRG

Description

Leucine-rich alpha-2-glycoprotein 1 (HGNC Symbol)

Entrez gene summary

The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

4536409 - 4540474

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171236 (version 78.38)

Entrez gene

116844

UniProt

P02750 (UniProt - Evidence at protein level)

neXtProt

NX_P02750

Antibodypedia

LRG1 antibodies


PROTEIN BROWSER

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ENST00000306390
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LRG1-001 ENSP00000302621
ENST00000306390
P02750
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