TSEN34

GENE INFORMATION

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Gene name

TSEN34 (HGNC Symbol)

Synonyms

LENG5, SEN34, SEN34L

Description

TSEN34 tRNA splicing endonuclease subunit (HGNC Symbol)

Entrez gene summary

This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Oct 2009]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

54189938 - 54194536

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170892 (version 78.38)

Entrez gene

79042

UniProt

Q9BSV6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BSV6

Antibodypedia

TSEN34 antibodies
 

PROTEIN VIEW

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TSEN34-001
 
TSEN34-003
 
TSEN34-004
 
TSEN34-005
 
TSEN34-006
 
TSEN34-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TSEN34-001 ENSP00000305524
ENST00000302937
Q9BSV6
Show all »
Show » Show » 310 33.7 No 0
TSEN34-003 ENSP00000379667
ENST00000396383
Q9BSV6
Show all »
Show » Show » 310 33.7 No 0
TSEN34-004 ENSP00000379671
ENST00000396388
Q9BSV6
Show all »
Show » Show » 310 33.7 No 0
TSEN34-005 ENSP00000408689
ENST00000456872
A9C4B9
Show all »
Show » Show » 251 27.3 No 0
TSEN34-006 ENSP00000400743
ENST00000455798
B0V3J0
Show all »
Show » Show » 242 26.1 No 0
TSEN34-201 ENSP00000397402
ENST00000429671
E7EQB3
Show all »
Show » Show » 315 34.3 No 0