PSG6

GENE INFORMATION

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Gene name

PSG6

Synonyms

Description

Pregnancy specific beta-1-glycoprotein 6 (HGNC Symbol)

Entrez gene summary

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Chromosome

19

Cytoband

Chromosome location (bp)

42728080 - 43205603

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170848 (version 78.38)

Entrez gene

5675

UniProt

Q00889 (UniProt - Evidence at transcript level)

neXtProt

NX_Q00889

Antibodypedia

PSG6 antibodies
 

PROTEIN VIEW

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PSG6-001
 
PSG6-002
 
PSG6-003
 
PSG6-006
 
PSG6-009
 
PSG6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSG6-001 ENSP00000187910
ENST00000187910
Q00889
Show all »
Show » Show » 424 47.5 Yes 0
PSG6-002 ENSP00000292125
ENST00000292125
Q00889
Show all »
Show » Show » 435 48.8 Yes 0
PSG6-003 ENSP00000385736
ENST00000402603
B5MCE1
Show all »
Show » Show » 331 36.7 Yes 0
PSG6-006 ENSP00000470412
ENST00000594375
M0QZA7
Show all »
Show » Show » 158 17.9 No 0
PSG6-009 ENSP00000469423
ENST00000601833
M0QXW0
Show all »
Show » 73 8.1 No 0
PSG6-201 ENSP00000482453
ENST00000621241
Show » Show » 401 44.6 Yes 1