PA2G4

GENE INFORMATION

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Gene name

PA2G4

Synonyms

Description

Proliferation-associated 2G4, 38kDa (HGNC Symbol)

Entrez gene summary

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.2

Chromosome location (bp)

56104319 - 56113907

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170515 (version 78.38)

Entrez gene

5036

UniProt

Q9UQ80 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UQ80

Antibodypedia

PA2G4 antibodies
 

PROTEIN VIEW

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PA2G4-001
 
PA2G4-008
 
PA2G4-009
 
PA2G4-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PA2G4-001 ENSP00000302886
ENST00000303305
Q9UQ80
Show all »
Show » Show » 394 43.8 No 0
PA2G4-008 ENSP00000447615
ENST00000553057
F8W0A3
Show all »
Show » Show » 187 20.2 No 0
PA2G4-009 ENSP00000447389
ENST00000551061
F8VZ69
Show all »
Show » 65 7.3 No 0
PA2G4-010 ENSP00000448557
ENST00000552766
F8VR77
Show all »
Show » Show » 284 31.5 No 0