EMX2

GENE INFORMATION

? »

Gene name

EMX2

Synonyms

Description

Empty spiracles homeobox 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009]

Chromosome

10

Cytoband

q26.11

Chromosome location (bp)

117542444 - 117549546

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170370 (version 78.38)

Entrez gene

2018

UniProt

Q04743 (UniProt - Evidence at protein level)

neXtProt

NX_Q04743

Antibodypedia

EMX2 antibodies
 

PROTEIN VIEW

? »
 
 
 
EMX2-001
 
EMX2-002
 
EMX2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EMX2-001 ENSP00000450962
ENST00000553456
Q04743
Show all »
Show » Show » 252 28.3 No 0
EMX2-002 ENSP00000480271
ENST00000616794
Show » 69 8.1 No 0
EMX2-201 ENSP00000474874
ENST00000442245
Q04743
Show all »
Show » Show » 169 18.5 No 0