SETMAR

GENE INFORMATION

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Gene name

SETMAR (HGNC Symbol)

Synonyms

metnase

Description

SET domain and mariner transposase fusion gene (HGNC Symbol)

Entrez gene summary

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

3

Cytoband

p26.1

Chromosome location (bp)

4303304 - 4317567

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170364 (version 78.38)

Entrez gene

6419

UniProt

Q53H47 (UniProt - Evidence at protein level)

neXtProt

NX_Q53H47

Antibodypedia

SETMAR antibodies
 

PROTEIN VIEW

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SETMAR-001
 
SETMAR-002
 
SETMAR-003
 
SETMAR-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SETMAR-001 ENSP00000373354
ENST00000358065
Q53H47
Show all »
Show » Show » 684 78 No 0
SETMAR-002 ENSP00000403000
ENST00000430981
Q53H47
Show all »
Show » Show » 365 40.5 No 0
SETMAR-003 ENSP00000369673
ENST00000358950
B9ZVV8
Show all »
Show » Show » 212 23.8 No 0
SETMAR-008 ENSP00000403145
ENST00000425863
Q53H47
Show all »
Show » Show » 545 62.1 No 0