TM4SF1

GENE INFORMATION

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Gene name

TM4SF1 (HGNC Symbol)

Synonyms

L6, M3S1

Description

Transmembrane 4 L six family member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q25.1

Chromosome location (bp)

149369022 - 149377865

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169908 (version 78.38)

Entrez gene

4071

UniProt

P30408 (UniProt - Evidence at protein level)

neXtProt

NX_P30408

Antibodypedia

TM4SF1 antibodies
 

PROTEIN VIEW

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TM4SF1-001
 
TM4SF1-003
 
TM4SF1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TM4SF1-001 ENSP00000304277
ENST00000305366
P30408
Show all »
Show » Show » 202 21.6 No 4
TM4SF1-003 ENSP00000417084
ENST00000472441
C9J611
Show all »
Show » Show » 117 12.5 No 1
TM4SF1-201 ENSP00000477606
ENST00000622124
Q8NE91
Show all »
Show » Show » 232 25.1 No 5