DCXR

GENE INFORMATION

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Gene name

DCXR (HGNC Symbol)

Synonyms

DCR, KIDCR, SDR20C1

Description

Dicarbonyl/L-xylulose reductase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

82035136 - 82037732

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169738 (version 78.38)

Entrez gene

51181

UniProt

Q7Z4W1 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z4W1

Antibodypedia

DCXR antibodies
 

PROTEIN VIEW

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DCXR-001
 
DCXR-006
 
DCXR-007
 
DCXR-010
 
DCXR-011
 
DCXR-015
 
DCXR-021
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCXR-001 ENSP00000303356
ENST00000306869
Q7Z4W1
Show all »
Show » Show » 244 25.9 No 0
DCXR-006 ENSP00000462226
ENST00000579155
J3KRZ4
Show all »
Show » Show » 141 14.9 No 0
DCXR-007 ENSP00000462272
ENST00000582900
J3KS22
Show all »
Show » Show » 224 24 No 0
DCXR-010 ENSP00000462725
ENST00000577712
Show » Show » 143 15 No 0
DCXR-011 ENSP00000464507
ENST00000581584
Show » Show » 225 23.5 No 0
DCXR-015 ENSP00000463354
ENST00000577532
J3QL34
Show all »
Show » Show » 176 18.9 No 0
DCXR-021 ENSP00000464332
ENST00000579004
Show » 86 9.2 No 0