CHRNA5

GENE INFORMATION

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Gene name

CHRNA5

Synonyms

Description

Cholinergic receptor, nicotinic, alpha 5 (neuronal) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]

Chromosome

15

Cytoband

q25.1

Chromosome location (bp)

78565520 - 78595269

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169684 (version 78.38)

Entrez gene

1138

UniProt

P30532 (UniProt - Evidence at transcript level)

neXtProt

NX_P30532

Antibodypedia

CHRNA5 antibodies
 

PROTEIN VIEW

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CHRNA5-001
 
CHRNA5-002
 
CHRNA5-003
 
CHRNA5-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRNA5-001 ENSP00000299565
ENST00000299565
P30532
Show all »
Show » Show » 468 53.1 Yes 4
CHRNA5-002 ENSP00000378281
ENST00000394802
Show » Show » 182 20.7 No 0
CHRNA5-003 ENSP00000453519
ENST00000559554
H0YM98
Show all »
Show » Show » 160 17.8 Yes 0
CHRNA5-004 ENSP00000452641
ENST00000559576
Show » Show » 56 6.2 No 0