Tissue expression of RBPJ - Summary - The Human Protein Atlas

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RBPJ

TISSUE

SUBCELL

CELL LINE

CANCER

TISSUE ATLAS

GENE/PROTEIN ANTIBODY/ANTIGEN


Dictionary

GENERAL INFORMATION ? »
Protein class Protein class the gene product belongs to according to selected gene lists. List of protein classes. Predicted localization Protein localization predicted from several bioinformatic algorithms. More info... Number of transcripts Number of protein-coding transcribed from this gene as defined by Ensembl.
Gene name	RBPJ
Gene description	Recombination signal binding protein for immunoglobulin kappa J region
Protein class	Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	22
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY ? »
Data reliability description Standardized explanatory sentences with additional information required for full understanding of the knowledge-based expression profile. Currently, not all genes have been analyzed by knowledge-based annotation, indicated by "Pending RNA-based expert annotation", when applicable. Data reliability Data reliability score (score description), divided into supportive (premium) or uncertain (not premium), is based on consistency between the staining pattern of one antibody or several antibodies with RNA-seq data and available gene/protein characterization data.
Data reliability	Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Lateral ventricle

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW ? »
Protein expression data is shown for each of the 44 tissues. Color-coding is based on 13 tissue groups, each consisting of tissues with common functional features. Mouse-over function shows protein score for analyzed cell types found in a selected tissue. To access image data click on tissue name or bar. Annotation of protein expression is described in detail in Assays & annotation. For genes with available protein data for which a knowledge-based annotation could not be performed, no protein expression data is displayed in the protein expression data overview, however, all immunohistochemical images are still available and the annotation data can be found under Primary data.
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

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HPA dataset

RNA tissue category:

Expressed in all

Organ

Expression

GTEx dataset

RNA tissue category:

Expressed in all

Organ

Expression

GENE INFORMATION ? »
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	RBPJ (HGNC Symbol)
Synonyms	CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH
Description	Recombination signal binding protein for immunoglobulin kappa J region (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Chromosome	4
Cytoband	p15.2
Chromosome location (bp)	26163455 - 26435131
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168214 (version 78.38)
Entrez gene	3516
UniProt	Q06330 (UniProt - Evidence at protein level)
neXtProt	NX_Q06330
Antibodypedia	RBPJ antibodies

PROTEIN BROWSER

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ENST00000342295		ENST00000342320		ENST00000345843		ENST00000348160		ENST00000355476		ENST00000361572		ENST00000504423		ENST00000504907		ENST00000504938		ENST00000505958		ENST00000506956		ENST00000507561		ENST00000507574		ENST00000509158		ENST00000510778		ENST00000511546		ENST00000512351		ENST00000512671		ENST00000514675		ENST00000514730		ENST00000514807		ENST00000515573

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)
RBPJ-001	ENSP00000305815 ENST00000345843	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:87%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:38%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:32%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	485	54.1	No
RBPJ-002	ENSP00000354528 ENST00000361572	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:85%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:37%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6R946 [Target identity:35%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423644} D6RBQ8 [Target identity:31%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:28%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	500	55.6	No
RBPJ-003	ENSP00000340124 ENST00000342320	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:87%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:38%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:32%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459} D6REC2 [Target identity:23%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425061} D6R9K5 [Target identity:22%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423575} D6R9X3 [Target identity:22%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RAT2 [Target identity:19%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RIZ8 [Target identity:19%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RF98 [Target identity:10%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:9%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:5%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	486	54.4	No
RBPJ-004	ENSP00000424789 ENST00000512351	D6RAT2 Show all » « Hide D6RAT2 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RF98 [Target identity:52%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:51%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	94	10.9	No
RBPJ-005	ENSP00000423644 ENST00000512671	D6R946 Show all » « Hide D6R946 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423644} D6RB37 [Target identity:80%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	178	20.2	No
RBPJ-006	ENSP00000426872 ENST00000505958	D6RE93 Show all » « Hide D6RE93 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		28	3.5	No
RBPJ-007	ENSP00000423907 ENST00000507561	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:91%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:40%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:33%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:30%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	465	51.9	No
RBPJ-010	ENSP00000423703 ENST00000504907	D6R927 Show all » « Hide D6R927 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423703} D6RA45 [Target identity:49%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:41%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:37%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459} D6REC2 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425061} D6R9K5 [Target identity:28%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423575} D6R9X3 [Target identity:28%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RIZ8 [Target identity:25%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RAT2 [Target identity:24%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6REP3 [Target identity:12%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RF98 [Target identity:12%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6RE93 [Target identity:7%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter]	382	43.5	No
RBPJ-011	ENSP00000425750 ENST00000506956	D6RIZ8 Show all » « Hide D6RIZ8 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RAT2 [Target identity:96%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RF98 [Target identity:50%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:49%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:28%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	97	11.3	No
RBPJ-012	ENSP00000424989 ENST00000514807	D6REP3 Show all » « Hide D6REP3 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:58%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	48	5.7	No
RBPJ-013	ENSP00000424804 ENST00000509158	D6RF98 Show all » « Hide D6RF98 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:97%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:57%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	49	5.8	No
RBPJ-014	ENSP00000425061 ENST00000514730	D6REC2 Show all » « Hide D6REC2 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425061} D6R9K5 [Target identity:97%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423575} D6R9X3 [Target identity:94%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RIZ8 [Target identity:85%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RAT2 [Target identity:83%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RF98 [Target identity:43%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:42%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:24%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	113	13.1	No
RBPJ-015	ENSP00000422617 ENST00000507574	D6RBQ8 Show all » « Hide D6RBQ8 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:91%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	157	17.9	No
RBPJ-016	ENSP00000423575 ENST00000514675	D6R9K5 Show all » « Hide D6R9K5 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423575} D6R9X3 [Target identity:97%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RIZ8 [Target identity:88%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RAT2 [Target identity:85%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RF98 [Target identity:44%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:43%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:25%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	110	12.8	No
RBPJ-017	ENSP00000423406 ENST00000515573	D6RA45 Show all » « Hide D6RA45 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:83%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:75%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter]	189	21.5	No
RBPJ-018	ENSP00000422838 ENST00000511546	D6R9X3 Show all » « Hide D6R9X3 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RIZ8 [Target identity:90%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RAT2 [Target identity:87%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RF98 [Target identity:45%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:44%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:26%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	107	12.4	No
RBPJ-020	ENSP00000424459 ENST00000504938	D6RB37 Show all » « Hide D6RB37 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated]	143	16.4	No
RBPJ-026	ENSP00000421804 ENST00000504423	H0Y8R3 Show all » « Hide H0Y8R3 [Target identity:100%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000421804}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter]	135	15.4	No
RBPJ-029	ENSP00000427170 ENST00000510778	D6RCM1 Show all » « Hide D6RCM1 [Target identity:99%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000427170} D6RBQ8 [Target identity:68%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:62%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter]	230	26.4	No
RBPJ-030	ENSP00000339699 ENST00000348160	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:87%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:38%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:32%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	487	54.3	No
RBPJ-201	ENSP00000345206 ENST00000342295	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:85%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:37%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6R946 [Target identity:35%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423644} D6RBQ8 [Target identity:31%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:28%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001228 [RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0001974 [blood vessel remodeling] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0002437 [inflammatory response to antigenic stimulus] GO:0003139 [secondary heart field specification] GO:0003151 [outflow tract morphogenesis] GO:0003157 [endocardium development] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0006959 [humoral immune response] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0008284 [positive regulation of cell proliferation] GO:0008285 [negative regulation of cell proliferation] GO:0009912 [auditory receptor cell fate commitment] GO:0009957 [epidermal cell fate specification] GO:0010467 [gene expression] GO:0010468 [regulation of gene expression] GO:0010628 [positive regulation of gene expression] GO:0021983 [pituitary gland development] GO:0030097 [hemopoiesis] GO:0030182 [neuron differentiation] GO:0030183 [B cell differentiation] GO:0030216 [keratinocyte differentiation] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035019 [somatic stem cell maintenance] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0042742 [defense response to bacterium] GO:0043011 [myeloid dendritic cell differentiation] GO:0043565 [sequence-specific DNA binding] GO:0045165 [cell fate commitment] GO:0045596 [negative regulation of cell differentiation] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0047485 [protein N-terminus binding] GO:0048505 [regulation of timing of cell differentiation] GO:0048733 [sebaceous gland development] GO:0048820 [hair follicle maturation] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060486 [Clara cell differentiation] GO:0060716 [labyrinthine layer blood vessel development] GO:0060844 [arterial endothelial cell fate commitment] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0072602 [interleukin-4 secretion] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:1901297 [positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	500	55.6	No
RBPJ-202	ENSP00000347659 ENST00000355476	Q06330 Show all » « Hide Q06330 [Direct mapping] Recombining binding protein suppressor of hairless A0A024R9Q8 [Target identity:87%; Query identity:100%] Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313\|EMBL:EAW92848.1} D6RA45 [Target identity:38%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423406} D6RBQ8 [Target identity:32%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422617} D6RB37 [Target identity:29%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424459} D6REC2 [Target identity:23%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425061} D6R9K5 [Target identity:22%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000423575} D6R9X3 [Target identity:22%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000422838} D6RAT2 [Target identity:19%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424789} D6RIZ8 [Target identity:19%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000425750} D6RF98 [Target identity:10%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424804} D6REP3 [Target identity:9%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000424989} D6RE93 [Target identity:5%; Query identity:100%] Recombining-binding protein suppressor of hairless {ECO:0000313\|Ensembl:ENSP00000426872}	Show » « Hide Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000150 [recombinase activity] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000982 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity] GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] GO:0001103 [RNA polymerase II repressing transcription factor binding] GO:0001525 [angiogenesis] GO:0001837 [epithelial to mesenchymal transition] GO:0002193 [MAML1-RBP-Jkappa- ICN1 complex] GO:0003151 [outflow tract morphogenesis] GO:0003160 [endocardium morphogenesis] GO:0003198 [epithelial to mesenchymal transition involved in endocardial cushion formation] GO:0003214 [cardiac left ventricle morphogenesis] GO:0003222 [ventricular trabecula myocardium morphogenesis] GO:0003256 [regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007219 [Notch signaling pathway] GO:0007221 [positive regulation of transcription of Notch receptor target] GO:0010467 [gene expression] GO:0030279 [negative regulation of ossification] GO:0030513 [positive regulation of BMP signaling pathway] GO:0035912 [dorsal aorta morphogenesis] GO:0036302 [atrioventricular canal development] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060045 [positive regulation of cardiac muscle cell proliferation] GO:0060716 [labyrinthine layer blood vessel development] GO:0061314 [Notch signaling involved in heart development] GO:0072554 [blood vessel lumenization] GO:0097101 [blood vessel endothelial cell fate specification] GO:1901186 [positive regulation of ERBB signaling pathway] GO:1901189 [positive regulation of ephrin receptor signaling pathway] GO:2000138 [positive regulation of cell proliferation involved in heart morphogenesis]	486	54.4	No

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.

Protein class

Predicted localization

Number of transcripts

RNA tissue category

Protein evidence

Protein localization

Data reliability description

Data reliability

RNA expression (FPKM)

Protein expression (score)

HPA dataset

RNA tissue category HPA

GTEx dataset

RNA tissue category GTEx