SRP68

GENE INFORMATION

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Gene name

SRP68

Synonyms

Description

Signal recognition particle 68kDa (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

76038775 - 76072653

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167881 (version 78.38)

Entrez gene

6730

UniProt

Q9UHB9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHB9

Antibodypedia

SRP68 antibodies
 

PROTEIN VIEW

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SRP68-001
 
SRP68-002
 
SRP68-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRP68-001 ENSP00000312066
ENST00000307877
Q9UHB9
Show all »
Show » Show » 627 70.7 No 0
SRP68-002 ENSP00000446136
ENST00000539137
Q9UHB9
Show all »
Show » Show » 589 66.1 No 0
SRP68-201 ENSP00000473613
ENST00000602720
Q9UHB9
Show all »
Show » Show » 288 32.9 No 0