KLK1

GENE INFORMATION

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Gene name

KLK1 (HGNC Symbol)

Synonyms

Klk6

Description

Kallikrein 1 (HGNC Symbol)

Entrez gene summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

50819148 - 50823787

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167748 (version 78.38)

Entrez gene

3816

UniProt

P06870 (UniProt - Evidence at protein level)

neXtProt

NX_P06870

Antibodypedia

KLK1 antibodies
 

PROTEIN VIEW

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KLK1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK1-001 ENSP00000301420
ENST00000301420
P06870
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