CDC42EP5

GENE INFORMATION

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Gene name

CDC42EP5 (HGNC Symbol)

Synonyms

Borg3, CEP5

Description

CDC42 effector protein (Rho GTPase binding) 5 (HGNC Symbol)

Entrez gene summary

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

54465026 - 54473264

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167617 (version 78.38)

Entrez gene

148170

UniProt

Q6NZY7 (UniProt - Evidence at protein level)

neXtProt

NX_Q6NZY7

Antibodypedia

CDC42EP5 antibodies
 

PROTEIN VIEW

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CDC42EP5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC42EP5-001 ENSP00000301200
ENST00000301200
Q6NZY7
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