CDT1

GENE INFORMATION

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Gene name

CDT1 (HGNC Symbol)

Synonyms

DUP, RIS2

Description

Chromatin licensing and DNA replication factor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]

Chromosome

16

Cytoband

q24.3

Chromosome location (bp)

88803213 - 88809258

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167513 (version 78.38)

Entrez gene

81620

UniProt

Q9H211 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H211

Antibodypedia

CDT1 antibodies
 

PROTEIN VIEW

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CDT1-001
 
CDT1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDT1-001 ENSP00000301019
ENST00000301019
Q9H211
Show all »
Show » Show » 546 60.4 No 0
CDT1-002 ENSP00000456926
ENST00000569140
Show » 190 20.9 No 0