NKX3-1

GENERAL INFORMATION

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Gene name

NKX3-1

Gene description

NK3 homeobox 1

Protein class

Cancer-related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (prostate)
GTEx:Group enriched (prostate, salivary gland)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (prostate)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (prostate, salivary gland)

Organ

Expression



GENE INFORMATION

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Gene name

NKX3-1 (HGNC Symbol)

Synonyms

BAPX2, NKX3.1, NKX3A

Description

NK3 homeobox 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]

Chromosome

8

Cytoband

p21.2

Chromosome location (bp)

23678693 - 23682927

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167034 (version 78.38)

Entrez gene

4824

UniProt

Q99801 (UniProt - Evidence at protein level)

neXtProt

NX_Q99801

Antibodypedia

NKX3-1 antibodies


PROTEIN BROWSER

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ENST00000380871
 
ENST00000523261
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NKX3-1-001 ENSP00000370253
ENST00000380871
Q99801
Show all »
Show » Show » 234 26.4 No 0
NKX3-1-004 ENSP00000429729
ENST00000523261
Q99801
Show all »
Show » Show » 159 18.4 No 0