CCNDBP1

GENE INFORMATION

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Gene name

CCNDBP1 (HGNC Symbol)

Synonyms

DIP1, GCIP

Description

Cyclin D-type binding-protein 1 (HGNC Symbol)

Entrez gene summary

This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]

Chromosome

15

Cytoband

q15.2

Chromosome location (bp)

43185118 - 43197176

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166946 (version 78.38)

Entrez gene

23582

UniProt

O95273 (UniProt - Evidence at protein level)

neXtProt

NX_O95273

Antibodypedia

CCNDBP1 antibodies
 

PROTEIN VIEW

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CCNDBP1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCNDBP1-001 ENSP00000300213
ENST00000300213
O95273
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