NAB2

GENE INFORMATION

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Gene name

NAB2 (HGNC Symbol)

Synonyms

MADER

Description

NGFI-A binding protein 2 (EGR1 binding protein 2) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.3

Chromosome location (bp)

57088894 - 57095476

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166886 (version 78.38)

Entrez gene

4665

UniProt

Q15742 (UniProt - Evidence at protein level)

neXtProt

NX_Q15742

Antibodypedia

NAB2 antibodies
 

PROTEIN VIEW

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NAB2-001
 
NAB2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NAB2-001 ENSP00000300131
ENST00000300131
Q15742
Show all »
Show » Show » 525 56.6 No 0
NAB2-002 ENSP00000341491
ENST00000342556
Q15742
Show all »
Show » Show » 461 49.7 No 0