MMP10

GENE INFORMATION

? »

Gene name

MMP10 (HGNC Symbol)

Synonyms

STMY2

Description

Matrix metallopeptidase 10 (stromelysin 2) (HGNC Symbol)

Entrez gene summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q22.2

Chromosome location (bp)

102770503 - 102780628

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166670 (version 78.38)

Entrez gene

4319

UniProt

P09238 (UniProt - Evidence at protein level)

neXtProt

NX_P09238

Antibodypedia

MMP10 antibodies
 

PROTEIN VIEW

? »
 
 
 
MMP10-001
 
MMP10-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MMP10-001 ENSP00000279441
ENST00000279441
P09238
Show all »
Show » Show » 476 54.2 Yes 0
MMP10-002 ENSP00000441485
ENST00000539681
F5GYX7
Show all »
Show » Show » 181 20.5 Yes 0