LMO1

GENE INFORMATION

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Gene name

LMO1 (HGNC Symbol)

Synonyms

RBTN1, RHOM1, TTG1

Description

LIM domain only 1 (rhombotin 1) (HGNC Symbol)

Entrez gene summary

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]

Chromosome

11

Cytoband

p15.4

Chromosome location (bp)

8224304 - 8268716

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000166407 (version 78.38)

Entrez gene

4004

UniProt

P25800 (UniProt - Evidence at transcript level)

neXtProt

NX_P25800

Antibodypedia

LMO1 antibodies
 

PROTEIN VIEW

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LMO1-001
 
LMO1-003
 
LMO1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LMO1-001 ENSP00000338207
ENST00000335790
P25800
Show all »
Show » Show » 156 17.8 No 0
LMO1-003 ENSP00000404538
ENST00000428101
P25800
Show all »
Show » Show » 155 17.7 No 0
LMO1-004 ENSP00000435456
ENST00000534484
E9PK83
Show all »
Show » Show » 145 16.6 No 0