CYB5R2

GENE INFORMATION

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Gene name

CYB5R2

Synonyms

Description

Cytochrome b5 reductase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Chromosome

11

Cytoband

p15.4

Chromosome location (bp)

7665100 - 7677222

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166394 (version 78.38)

Entrez gene

51700

UniProt

Q6BCY4 (UniProt - Evidence at protein level)

neXtProt

NX_Q6BCY4

Antibodypedia

CYB5R2 antibodies
 

PROTEIN VIEW

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CYB5R2-001
 
CYB5R2-003
 
CYB5R2-004
 
CYB5R2-006
 
CYB5R2-007
 
CYB5R2-009
 
CYB5R2-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYB5R2-001 ENSP00000437041
ENST00000533558
Q6BCY4
Show all »
Show » Show » 276 31.5 No 0
CYB5R2-003 ENSP00000299498
ENST00000299498
Q6BCY4
Show all »
Show » Show » 276 31.5 No 0
CYB5R2-004 ENSP00000435916
ENST00000524790
Q6BCY4
Show all »
Show » Show » 237 27 No 0
CYB5R2-006 ENSP00000432482
ENST00000524608
E9PQW2
Show all »
Show » Show » 189 21.5 No 1
CYB5R2-007 ENSP00000434969
ENST00000531096
E9PMI2
Show all »
Show » Show » 171 19.4 No 0
CYB5R2-009 ENSP00000433856
ENST00000527542
E9PIV9
Show all »
Show » Show » 146 16.8 No 0
CYB5R2-010 ENSP00000392777
ENST00000436351
E9PRM4
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Show » Show » 116 13.4 No 0