DDX21

GENE INFORMATION

? »

Gene name

DDX21 (HGNC Symbol)

Synonyms

GURDB, RH-II/GU

Description

DEAD (Asp-Glu-Ala-Asp) box helicase 21 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q22.1

Chromosome location (bp)

68956128 - 68985073

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165732 (version 78.38)

Entrez gene

9188

UniProt

Q9NR30 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR30

Antibodypedia

DDX21 antibodies
 

PROTEIN VIEW

? »
 
 
 
DDX21-001
 
DDX21-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX21-001 ENSP00000346120
ENST00000354185
Q9NR30
Show all »
Show » Show » 783 87.3 No 0
DDX21-201 ENSP00000480334
ENST00000620315
Q9NR30
Show all »
Show » Show » 715 79.7 No 0