GFI1B

GENE INFORMATION

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Gene name

GFI1B

Synonyms

Description

Growth factor independent 1B transcription repressor (HGNC Symbol)

Entrez gene summary

This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Chromosome

9

Cytoband

q34.13

Chromosome location (bp)

132945551 - 132991696

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165702 (version 78.38)

Entrez gene

8328

UniProt

Q5VTD9 (UniProt - Evidence at protein level)

neXtProt

NX_Q5VTD9

Antibodypedia

GFI1B antibodies
 

PROTEIN VIEW

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GFI1B-001
 
GFI1B-002
 
GFI1B-003
 
GFI1B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GFI1B-001 ENSP00000361196
ENST00000372123
Q5VTD9
Show all »
Show » Show » 284 32.4 No 0
GFI1B-002 ENSP00000361195
ENST00000372122
Q5VTD9
Show all »
Show » Show » 330 37.5 No 0
GFI1B-003 ENSP00000344782
ENST00000339463
Q5VTD9
Show all »
Show » Show » 330 37.5 No 0
GFI1B-201 ENSP00000446134
ENST00000534944
Q5VTD9
Show all »
Show » Show » 284 32.4 No 0