ATP5C1

GENE INFORMATION

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Gene name

ATP5C1 (HGNC Symbol)

Synonyms

ATP5C, ATP5CL1

Description

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

7788129 - 7807815

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165629 (version 78.38)

Entrez gene

509

UniProt

P36542 (UniProt - Evidence at protein level)

neXtProt

NX_P36542

Antibodypedia

ATP5C1 antibodies
 

PROTEIN VIEW

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ATP5C1-001
 
ATP5C1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP5C1-001 ENSP00000349142
ENST00000356708
P36542
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Show » Show » 298 33 No 0
ATP5C1-002 ENSP00000338568
ENST00000335698
P36542
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Show » Show » 297 32.9 No 0