ARF6

GENE INFORMATION

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Gene name

ARF6

Synonyms

Description

ADP-ribosylation factor 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q21.3

Chromosome location (bp)

49893092 - 49897054

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165527 (version 78.38)

Entrez gene

382

UniProt

P62330 (UniProt - Evidence at protein level)

neXtProt

NX_P62330

Antibodypedia

ARF6 antibodies
 

PROTEIN VIEW

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ARF6-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARF6-001 ENSP00000298316
ENST00000298316
P62330
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