FIGF

GENE INFORMATION

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Gene name

FIGF (HGNC Symbol)

Synonyms

VEGF-D, VEGFD

Description

C-fos induced growth factor (vascular endothelial growth factor D) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

15345591 - 15384376

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165197 (version 78.38)

Entrez gene

2277

UniProt

O43915 (UniProt - Evidence at protein level)

neXtProt

NX_O43915

Antibodypedia

FIGF antibodies
 

PROTEIN VIEW

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FIGF-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FIGF-001 ENSP00000297904
ENST00000297904
O43915
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