TMC1

GENE INFORMATION

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Gene name

TMC1 (HGNC Symbol)

Synonyms

DFNA36, DFNB11, DFNB7

Description

Transmembrane channel-like 1 (HGNC Symbol)

Entrez gene summary

This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q21.13

Chromosome location (bp)

72521801 - 72836351

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165091 (version 78.38)

Entrez gene

117531

UniProt

Q8TDI8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TDI8

Antibodypedia

TMC1 antibodies
 

PROTEIN VIEW

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TMC1-001
 
TMC1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMC1-001 ENSP00000297784
ENST00000297784
Q8TDI8
Show all »
Show » Show » 760 87.8 No 9
TMC1-201 ENSP00000341433
ENST00000340019
Q8TDI8
Show all »
Show » Show » 760 87.8 No 9